Mazindol Lose Generic Name: mazindol (MA zin doll) Brand Names: IFA LOSE What is mazindol? Mazindol is a sympathomimetic amine, which is similar to an amphetamine. It is also known as an “anorectic” or an “anorexigenic” drug. Mazindol stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. Mazindol Lose is used as a short-term supplement to diet and exercise in the treatment of obesity. Mazindol may also be used for other purposes.